The Key to Longevity Lies in Vascular Health: “It’s Not Age, It’s Vascular Age”

Longevity is determined not by chronological age, but by vascular health. According to Prof. Dr. Kerim Güler, when risk factors such as diabetes, obesity, and hypertension coexist, health risks can increase by up to 60 times. Experts emphasize the importance of early intervention and lifestyle management.

Continuing its investments in health and wellness, TAB İlaç introduced its new-generation vitamin group TABVITAMINS at its 15th anniversary event. During the “Eat Less, Live Longer” session, Prof. Dr. Kerim Güler, Chairman of the Turkish Society of Internal Medicine Specialists, underlined that vascular health is the primary determinant of longevity.

Endothelium: The Body’s Hidden Key Organ

Prof. Dr. Güler emphasized the importance of the endothelium, the inner lining of all blood and lymph vessels, which is now considered a vital organ. Weighing approximately 1.5 kilograms and covering up to 800 square meters when expanded, it is one of the largest functional systems in the human body.

He noted that vital organs such as the heart, brain, and kidneys are directly affected by vascular health, and even minor disruptions in circulation can lead to serious consequences.

Even Minor Blockages Pose Major Risks

Highlighting the damaging effects of diabetes, hypertension, and smoking on vascular structures, Güler stressed that uninterrupted blood flow is essential for organ function.

“Even the smallest blockage in the vascular system can lead to severe health problems,” he said, pointing to obesity and sedentary lifestyles as key contributing factors.

Compounded Risk from Multiple Factors

Güler provided striking data on the combined impact of multiple risk factors:

  • Diabetes + hypertension + high LDL cholesterol → risk increases 20-fold
  • Adding obesity to this combination → risk rises to 60-fold

“Obesity sits at the center of this risk chain,” Güler stated, emphasizing the critical importance of weight management.

A Critical Outlook for Türkiye

In Türkiye, the failure rate in hypertension control stands at 46%, placing the country behind European averages. Güler also noted that 345 people die daily from their first heart attack, with most cases linked to preventable risk factors.

Globally, it is estimated that by 2030, nearly 3 billion people will have a high body mass index, posing a significant burden on healthcare systems.

“Aging Is Largely Controllable”

Prof. Dr. Güler emphasized that aging can be managed to a significant extent:

“A person’s age should be measured not chronologically, but by vascular age. Diabetes can be treated, hypertension can be controlled, and smoking can be stopped. Protecting the endothelium is the key to longevity.”

Nutrition and Supplements Play a Key Role

Addressing the impact of nutrition, Güler highlighted the benefits of the Mediterranean diet in maintaining vascular health:

  • Cruciferous vegetables and berries help reduce inflammation
  • Whole grains and legumes support metabolic balance
  • Olive oil lowers CRP and IL-6 levels

He also noted that supplements such as berberine may support blood sugar regulation and cholesterol balance.

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